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Diabetes Medications

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Healthier Life by Addressing Hyperlipidemia

Lipids are fats that exist in the blood. We all have them, and it is unhealthy to live with elevated levels of certain lipids, including triglycerides and LDL cholesterol. Physicians perform blood tests to measure lipid levels—that's the easy part. For patients who learn they have elevated lipid levels, or hyperlipidemia, the hard part is doing what is required to bring them down.

Your doctors will consider many treatments to help you reduce the unhealthy levels of fat in your blood. One effective treatment with low risk of side effects is changing a patient's lifestyle. Altering diets and increasing exercise and activity levels can often produce amazing results and eliminate hyperlipidemia. It also makes you feel great.

A second treatment option are statins. Statins are lipid lowering drugs that have proven effective for decades now. However, they have their risks and side effects. We recommend a patient use statins in conjunction with proper diet and exercise. The combined effect is powerful, and can reverse diabetes and heart disease in many patients. Your physician can help you know if a statin could be an effective treatment for you.

If your physician diagnoses you with hyperlipidemia, you will need to set some goals for yourself. You want to do the work required to return to the physician a few months later for impoved bloodwork results. Your targets are:

  • A total cholesterol level of less than 200 mg per dL
  • Triglyceride levels less than 150 mg per dL
  • LDL (bad cholesterol) levels less than 100 mg per dL

Once you have achieved those goals, we hope exercise and your new diet help you continue maintaining healthy lipid levels.

Sources:
American Academy of Family Practice
National Institutes of Health
Cleveland Clinic

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Finding The Right Time to Start Insulin

There are a number of opinions about when to start insulin therapy. Certainly you will make your decision based on your situation. If you are a type 1 diabetic, you probably started insulin therapy minutes after your diagnosis. If you are a type 2 diabetic with tightly managed blood sugar, you may not need insulin for decades. Regardless of your circumstances, insulin may be the second-best blood sugar management tool. (Lifestyle management is the best.)

When to begin using insulin is a tough decision for people living with type 2 diabetes. Many members of the medical community are conservative about prescribing medications. There are some physicians who wait to introduce insulin until their patients get to a place in their life where ketoacidosis could be a risk. On the other hand, introducing insulin when blood sugar levels are on the low end of the diabetic spectrum can be dangerous. Insulin can contribute to hypoglycemia by removing sugar too aggressively from the bloodstream, thereby starving muscles, brain cells, and other vital body tissues.

According to the American Diabetes Association (ADA) Standards of Medical Care, a person who cannot maintain their A1C level below 7 percent should initiate insulin therapy. Your physician may try a number of medications before trying insulin, but it is not likely he or she will allow you to maintain high blood sugar levels over a long period of time. High blood sugar indicates your pancreas cannot keep up with your insulin demands, and you need to supplement. The ADA also points out that in extreme circumstances, patients may start insulin early on in the disease process. In its document Standards of Medical Care it states:

Early initiation of insulin would be a safer approach for individuals presenting with weight loss, more severe symptoms, and glucose values of 250-300 mg/dL.

 

When you give yourself an insulin shot you are actually substituting for your pancreas. When medications and lifestyle can no longer control your blood sugar, it's time to let insulin therapy substitute for your pancreas. Insulin may help you live and feel better.

I'm Concerned About the Weight I'll Probably Gain with Insulin

Many people using insulin gain weight. We at My Diabetes Information are pro-insulin. We suspect a lot of people start it too late. Nevertheless, the weight gain is a concern because more weight increases the odds of a number of heart-related health risks—risks already associated with diabetes. Furthermore, extra weight causes angst because of the way it makes us look and feel. Those concerns are legitimate.

Medical professionals are also concerned about the health risks associated with additional pounds. Nevertheless, high blood sugar is usually a more serious health risk than extra weight. You should almost always prefer to use insulin—when the time is right—instead of staying thinner. Of course you should discuss this balancing act with your doctor.

Januvia May Offer Alternative Option for Treating Type 2 Diabetes

CHICAGO—People are justly concerned about the safety of the medications they take. When new medications come to market, we have a reasonably good indication that they are safe thanks to the U.S. Food and Drug Administration review process. Still there are too many surprises that emerge in the few medications that turn out to be harmful.

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Conflicting Interpretations of Data for Diabetes Medication Rosiglitazone

Because of the uproar in the diabetes community fueled by a New England Journal of Medicine (NEJM) last week, the publication decided to release some preliminary findings in an article about an additional study on rosiglitazone (brand name Avandia). But even these preliminary findings are open to a lot of interpretation, and audiences are drawing different conclusions . One of todays' headlines read Diabetes drugmaker cites "reassuring" study, while another national media outlet captioned with Newest Avandia Study Not Reassuring. Even in the New England Journal of Medicine there were three different editorial pieces, all putting forth different interpretations of this data. Keep in mind that this is only preliminary.

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Japanese Diabetes Drug May Take Four Years to Make it to USA

A drug company can decide which countries it wants to introduce its drugs into first. Here in the United States, we assume drug companies will introduce them here first. Usually American drug companies introduce drugs in the United States. But drug companies in Europe often apply for approval there. The same holds true with Japan, Israel, and other counties where there are quite a few drug-producing companies.

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Do Not Fly Solo on Diabetes Medication Changes

Because of the recent news about rosiglitazone (brand name Avandia), people are wondering if they should stop taking it right away. According Maria Collazo-Clavell, M.D., of the Mayo Clinic it is a mistake to just drop it. You should consider any changes under the supervision of your doctor.

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Happy 85th to the diabetes miracle - insulin

An article in April's edition of Diabetes Research and Clinical Practice celebrates the 85th birthday of insulin. Now, those of you that inject it every day, or maintain an insulin pump, may not always want to celebrate insulin's birthday. After all, it is part of the rigmarole, and we understand. Still, insulin is better than the alternatives that existed prior to 1922. Before insulin came along, people with type 1 diabetes would often only last for a few months beyond their initial diagnosis. Type 2 diabetics could often manage quite a bit longer with a very strict diet.

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Diabetics not singing along - now it's the inhaled insulin blues

Very few people with diabetes are using inhaled insulin. It also appears that the doctors may lack enthusiasm for inhaled insulin. They are not ordering the lung function test that many patients need to assure they have the lung capacity to handle it. After a significant number of asthma-like events occurred during the clinical trial, researchers found that inhaled insulin can reduce lung capacity.

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FDA Approves New Prefilled Disposable Lantus Pen

Paris, France - April 30, 2007 - Sanofi-aventis announced today that the U.S. Food and Drug Administration (FDA) approved SoloSTAR, a new prefilled disposable insulin pen for once daily 24-hour insulin LANTUS (insulin glargine) for the treatment of hyperglycemia in people with type 1 or type 2 diabetes. The introduction of LANTUS SoloSTAR offers a convenient option for administering once-daily 24-hour LANTUS. LANTUS in the SoloSTAR pen provides diabetes patients with an alternative to the traditional needle and syringe for insulin therapy. SoloSTAR is a prefilled, disposable insulin pen that allows patients to dial their dose from one to 80 units of insulin.

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Pre-diabetes as people instead of type 2 diabetes patients

We are pleased that doctors and diabetes experts are thinking about the future, and pointing out where our medical establishment might be leading people to take pills instead of modifying their lifestyle. Writing in BMJ, three respected diabetes authorities make the argument that changing lifestyle should be the mainstay of preventing type 2 diabetes rather than prescribing medication to people with pre-diabetes and impaired glucose tolerance.

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