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Small Advantages of Weight Loss Drugs

Weight loss drugs may be helping people with diabetes. Rimonabant is still in clinical trial, but users experienced better blood sugar management. Similar blood sugar results occured with over-the-counter orlistat.

The two weight loss drugs currently on the market only have a minor effect on weight according to the latest research. A new drug that has not yet been approved, rimonabant, seems to be a little more effective than it's rivals. However, concerns over common behavioral health side effects have kept it out of pharmacies so far.

A team of researchers from Canada and Brazil published an article in the British Medical Journal presenting the findings of 30 weight loss drug clinical trials . They concluded:

  • Sibutramine clinical trial participants lost an average of 9.3 pounds. They also experienced lower triglyceride levels. Unfortunately, researchers observed higher blood pressure among sibutramine users. 
  • While orlistat delivered the least weight loss at an average of 6.4 pounds, its other health benefits were impressive. Orlistat reduced blood sugar measures, lowered LDL cholesterol and improved blood pressure. However, orlistat users reported uncomfortable digestive system side effects like diarrhea.

Most patients taking medications that cause weight loss dropped 5 to 10 percent of their body weight. However, miraculous weight loss does not occur with most patients. Weight loss is a miracle you create yourself. It requires patience, time, discipline, and sacrifice.

Sources:

BMJ, November 2007

Washington Post, November 2007

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